difluprednate

0.5 MG — Drops

Ophthalmic Anti-inflammatories

Also known as: Durezol
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Coverage by Insurer

Informational only — Coverage rules change frequently; verify tier placement and restrictions with your plan or pharmacy before acting.
Source: CMS QHP JSON  ·  Formulary date: Jan 1, 2026  ·  Checked: 7 hours, 58 minutes ago
Plan Tier Prior Auth Step Therapy Quantity Limit Restrictions
Everyday Bronze with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Elite Bronze with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Focused Silver with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Complete Gold with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Expanded Bronze + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Silver with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Gold + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Silver + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Gold with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Standard Expanded Bronze with Atrium Health + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Complete Gold Tier 2 - Generic ✓ — — PA
Enhanced Asthma/COPD Care Silver with $0 Drug Options Tier 2 - Generic ✓ — — PA
Everyday Bronze Tier 2 - Generic ✓ — — PA
Elite Bronze Tier 2 - Generic ✓ — — PA
Clear Silver with $0 Insulin Options Tier 2 - Generic ✓ — — PA
Standard Expanded Bronze Tier 2 - Generic ✓ — — PA
Standard Silver Tier 2 - Generic ✓ — — PA
Standard Gold Tier 2 - Generic ✓ — — PA
Everyday Bronze with Atrium Health Tier 2 - Generic ✓ — — PA
Elite Bronze with Atrium Health Tier 2 - Generic ✓ — — PA
Focused Silver with Atrium Health Tier 2 - Generic ✓ — — PA
Complete Gold with Atrium Health Tier 2 - Generic ✓ — — PA
Standard Expanded Bronze with Atrium Health Tier 2 - Generic ✓ — — PA
Standard Silver with Atrium Health Tier 2 - Generic ✓ — — PA
Standard Gold with Atrium Health Tier 2 - Generic ✓ — — PA
Enhanced Asthma/COPD Care Silver with $0 Drug Options + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Complete Gold + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Everyday Bronze + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Elite Bronze + Vision + Adult Dental Tier 2 - Generic ✓ — — PA
Source: PDF  ·  Formulary date: Apr 1, 2026  ·  Checked: 7 hours, 58 minutes ago
Plan Tier Prior Auth Step Therapy Quantity Limit Restrictions
BCBSNC Blue Home with UNC Health Alliance 2026
via Durezol 		Tier 2 - Medium Cost Generic/Brand — — — None
BCBSNC Blue Local 2026
via Durezol 		Tier 2 - Medium Cost Generic/Brand — — — None
BCBSNC Blue Value 2026
via Durezol 		Tier 2 - Medium Cost Generic/Brand — — — None
BCBSNC Blue Care 2026
via Durezol 		Tier 2 - Medium Cost Generic/Brand — — — None
BCBSNC Blue Advantage 2026
via Durezol 		Tier 2 - Medium Cost Generic/Brand — — — None
Source: CMS QHP JSON  ·  Formulary date: Mar 18, 2026  ·  Checked: 7 hours, 57 minutes ago
Plan Tier Prior Auth Step Therapy Quantity Limit Restrictions
Liberty Medicare Dual Plan (HMO D-SNP) Tier 1 - Preferred Generic — — — None
Liberty Medicare Advantage Nursing Home Plan (HMO I-SNP) Tier 1 - Preferred Generic — — — None
PruittHealth Premier (HMO I-SNP) Tier 1 - Preferred Generic — — — None
NHC Advantage (HMO I-SNP) Tier 1 - Preferred Generic — — — None
Liberty Medicare Advantage (HMO C-SNP) Tier 2 - Generic — — — None
Troy Medicare (HMO) Tier 2 - Generic — — — None
Troy Medicare for Dual-eligible Beneficiaries (HMO D-SNP) Tier 2 - Generic — — — None
AmeriHealth Caritas VIP Care (HMO D-SNP) Tier 2 - Generic — — — None
Senior Care (HMO I-SNP) Tier 2 - Generic — — — None
Alignment Health Platinum Select (HMO) Tier 3 - Preferred Brand — — — None
Alignment Health AVA (PPO) Tier 3 - Preferred Brand — — — None
HealthSpring True Choice (PPO) Tier 3 - Preferred Brand — — — None
HealthSpring TotalCare (HMO D-SNP) Tier 3 - Preferred Brand — — — None
HealthSpring TotalCare Plus (HMO D-SNP) Tier 3 - Preferred Brand — — — None
HealthSpring Preferred (HMO) Tier 3 - Preferred Brand — — — None
Alignment Health Heart & Diabetes Care (HMO C-SNP) Tier 3 - Preferred Brand — — — None
HealthSpring Preferred Select (HMO) Tier 3 - Preferred Brand — — — None
HealthSpring Preferred Savings (HMO) Tier 3 - Preferred Brand — — — None
HealthSpring Preferred Plus (HMO) Tier 3 - Preferred Brand — — — None
Alignment Health Platinum (HMO) Tier 3 - Preferred Brand — — — None
Alignment Health NC Duals (HMO-POS D-SNP) Tier 3 - Preferred Brand — — — None
Alignment Health smartHMO (HMO) Tier 3 - Preferred Brand — — — None
Alignment Health Heart & Diabetes NCPlus (HMO-POS C-SNP) Tier 3 - Preferred Brand — — — None
Blue Medicare Choice (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Dual (HMO D-SNP) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Value Plus (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Prime (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature Care (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Full Dual Care (HMO D-SNP) Tier 4 - Non-Preferred — — — None
Aetna Medicare Enhanced (HMO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Enhanced (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Enhanced (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature Extra (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature Giveback (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Signature (PPO) Tier 4 - Non-Preferred — — — None
Aetna Medicare Chronic Care (HMO C-SNP) Tier 4 - Non-Preferred — — — None
Aetna Medicare Chronic Care Value (HMO C-SNP) Tier 4 - Non-Preferred — — — None
DEVOTED DUAL PLUS 006 NC (HMO D-SNP) Tier 4 - Non-Preferred — — — None
DEVOTED DUAL 009 NC (HMO D-SNP) Tier 4 - Non-Preferred — — — None
DEVOTED CORE 001 NC (HMO) Tier 4 - Non-Preferred — — — None
DEVOTED GIVEBACK 002 NC (HMO) Tier 4 - Non-Preferred — — — None
DEVOTED GIVEBACK 012 NC (HMO) Tier 4 - Non-Preferred — — — None
Wellcare Simple Open (PPO) Tier 4 - Non-Preferred — — — None
Wellcare Simple (HMO-POS) Tier 4 - Non-Preferred — — — None
Wellcare Giveback Open (PPO) Tier 4 - Non-Preferred — — — None
Blue Medicare PPO Enhanced (PPO) Tier 4 - Non-Preferred — — — None
Blue Medicare Essential Plus (HMO-POS) Tier 4 - Non-Preferred — — — None
Blue Medicare Enhanced (HMO-POS) Tier 4 - Non-Preferred — — — None
Blue Medicare Essential (HMO) Tier 4 - Non-Preferred — — — None
Experience Health Medicare Advantage (HMO) Tier 4 - Non-Preferred — — — None
Healthy Blue + Medicare (HMO-POS D-SNP) Tier 4 - Non-Preferred — — — None
Wellcare Dual Liberty Open (PPO D-SNP) Tier 4 - Non-Preferred — — — None
Wellcare Assist Open (PPO) Tier 4 - Non-Preferred — — — None
Wellcare Dual Access (HMO-POS D-SNP) Tier 4 - Non-Preferred — — — None
Wellcare Dual Liberty (HMO-POS D-SNP) Tier 4 - Non-Preferred — — — None
Wellcare Dual Reserve (HMO-POS D-SNP) Tier 4 - Non-Preferred — — — None
Source: PDF  ·  Formulary date: Apr 1, 2026  ·  Checked: 7 hours, 57 minutes ago
Plan Tier Prior Auth Step Therapy Quantity Limit Restrictions
NC Medicaid Preferred Drug List 2026 Preferred — — — None
NC Medicaid Preferred Drug List 2026
via Durezol 		Non-Preferred — — — None
Source: PDF  ·  Formulary date: Jan 1, 2026  ·  Checked: 7 hours, 57 minutes ago
Plan Tier Prior Auth Step Therapy Quantity Limit Restrictions
UnitedHealthcare NC Individual & Family 2026 Tier 4 - Higher Cost — — — None
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