Rebif Rebidose

Generic: interferon beta-1a

22MCG/0.5ML, 44MCG/0.5ML — Auto-Injector

Also known as: REBIF REBIDOSE SOAJ 22MCG/0.5ML, 44MCG/0.5ML

Coverage by Insurer

Informational only — Coverage rules change frequently; verify tier placement and restrictions with your plan or pharmacy before acting.

Ambetter (Centene)

58 plans

Source: CMS QHP JSON · Formulary date: Jan 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
Standard Gold via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Enhanced Asthma/COPD Care Silver with $0 Drug Options via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Clear Silver with $0 Insulin Options via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Focused Silver with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold with Atrium Health via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Enhanced Asthma/COPD Care Silver with $0 Drug Options + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Focused Silver with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold with Atrium Health + Vision + Adult Dental via Avonex	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Enhanced Asthma/COPD Care Silver with $0 Drug Options via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Clear Silver with $0 Insulin Options via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Focused Silver with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold with Atrium Health via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Enhanced Asthma/COPD Care Silver with $0 Drug Options + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Everyday Bronze with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Elite Bronze with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Focused Silver with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Complete Gold with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Expanded Bronze with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Silver with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL
Standard Gold with Atrium Health + Vision + Adult Dental via Rebif	Tier 5 - Specialty	✓	—	✓	PA \| QL

Blue Cross Blue Shield Federal

9 plans

Source: PDF · Formulary date: Apr 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
BCBS Federal Focus 2026 via Rebif	Tier 2 - Preferred Brand	✓	—	—	PA
BCBS Federal Focus 2026	Tier 2 - Preferred Brand	✓	—	—	PA
BCBS Federal Focus 2026 via Avonex	Tier 2 - Preferred Brand	✓	—	—	PA
BCBS Federal Standard Option 2026 via Avonex	Tier 4 - Preferred Specialty	✓	—	—	PA
BCBS Federal Standard Option 2026 via Rebif	Tier 4 - Preferred Specialty	✓	—	—	PA
BCBS Federal Standard Option 2026	Tier 4 - Preferred Specialty	✓	—	—	PA
BCBS Federal Basic Option 2026 via Avonex	Tier 4 - Preferred Specialty	✓	—	—	PA
BCBS Federal Basic Option 2026 via Rebif	Tier 4 - Preferred Specialty	✓	—	—	PA
BCBS Federal Basic Option 2026	Tier 4 - Preferred Specialty	✓	—	—	PA

Blue Cross Blue Shield of NC

15 plans

Source: PDF · Formulary date: Apr 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
BCBSNC Blue Local 2026 via Rebif	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Care 2026 via Rebif	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Value 2026 via Rebif	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Advantage 2026	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Home with UNC Health Alliance 2026	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Local 2026	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Care 2026	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Advantage 2026 via Avonex	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Value 2026	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Home with UNC Health Alliance 2026 via Avonex	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Local 2026 via Avonex	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Care 2026 via Avonex	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Value 2026 via Avonex	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Advantage 2026 via Rebif	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL
BCBSNC Blue Home with UNC Health Alliance 2026 via Rebif	Tier 5 - Specialty	✓	—	✓ Restricted Access	PA \| QL

Cigna

1 plan

Source: PDF · Formulary date: Jan 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
Cigna Plus NC 4-Tier Formulary 2026 via Avonex	Tier 4 - Specialty	✓	—	— Specialty Pharmacy Required	PA

Medicare Part D

31 plans

Source: CMS QHP JSON · Formulary date: Mar 18, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
Liberty Medicare Dual Plan (HMO D-SNP) via Avonex	Tier 1 - Preferred Generic	—	—	✓ 1 per 28 days	QL
Provider Partners North Carolina Essential Plan (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	✓	—	✓ 4 per 28 days	PA \| QL
Provider Partners North Carolina Advantage Plan (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	✓	—	✓ 4 per 28 days	PA \| QL
Longevity Health Plan (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	✓	—	✓ 1 per 28 days	PA \| QL
Provider Partners North Carolina Essential Plan (HMO I-SNP) via Rebif	Tier 1 - Preferred Generic	✓	—	✓ 8.40 per 365 days	PA \| QL
Provider Partners North Carolina Community Plan (HMO I-SNP) via Rebif	Tier 1 - Preferred Generic	✓	—	✓ 8.40 per 365 days	PA \| QL
Provider Partners North Carolina Advantage Plan (HMO I-SNP) via Rebif	Tier 1 - Preferred Generic	✓	—	✓ 8.40 per 365 days	PA \| QL
NHC Advantage (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	—	—	✓ 1 per 28 days	QL
PruittHealth Premier (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	—	—	✓ 1 per 28 days	QL
Liberty Medicare Advantage Nursing Home Plan (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	—	—	✓ 1 per 28 days	QL
Provider Partners North Carolina Community Plan (HMO I-SNP) via Avonex	Tier 1 - Preferred Generic	✓	—	✓ 4 per 28 days	PA \| QL
Troy Medicare (HMO) via Rebif	Tier 5 - Specialty	✓	—	—	PA
Liberty Medicare Advantage (HMO C-SNP) via Avonex	Tier 5 - Specialty	—	—	✓ 1 per 28 days	QL
Blue Medicare PPO Enhanced (PPO) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Blue Medicare Essential Plus (HMO-POS) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Blue Medicare Enhanced (HMO-POS) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Blue Medicare Choice (HMO) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Blue Medicare Essential (HMO) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Experience Health Medicare Advantage (HMO) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
Healthy Blue + Medicare (HMO-POS D-SNP) via Avonex	Tier 5 - Specialty	✓	—	✓ 1 per 28 days	PA \| QL
HealthTeam Advantage Plan I (PPO) via Rebif	Tier 5 - Specialty	✓	—	✓ 8.40 per 365 days	PA \| QL
HealthTeam Advantage Plan II (PPO) via Rebif	Tier 5 - Specialty	✓	—	✓ 8.40 per 365 days	PA \| QL
HealthTeam Advantage Vitality Plan (PPO) via Rebif	Tier 5 - Specialty	✓	—	✓ 8.40 per 365 days	PA \| QL
HealthTeam Advantage Plan I (PPO) via Avonex	Tier 5 - Specialty	✓	—	✓ 4 per 28 days	PA \| QL
HealthTeam Advantage Plan II (PPO) via Avonex	Tier 5 - Specialty	✓	—	✓ 4 per 28 days	PA \| QL
HealthTeam Advantage Vitality Plan (PPO) via Avonex	Tier 5 - Specialty	✓	—	✓ 4 per 28 days	PA \| QL
HealthTeam Advantage Diabetes & Heart Care (HMO C-SNP) via Rebif	Tier 5 - Specialty	✓	—	✓ 8.40 per 365 days	PA \| QL
HealthTeam Advantage Diabetes & Heart Care (HMO C-SNP) via Avonex	Tier 5 - Specialty	✓	—	✓ 4 per 28 days	PA \| QL
Troy Medicare for Dual-eligible Beneficiaries (HMO D-SNP) via Rebif	Tier 5 - Specialty	✓	—	—	PA
Senior Care (HMO I-SNP) via Avonex	Tier 5 - Specialty	—	—	✓ 1 per 28 days	QL
AmeriHealth Caritas VIP Care (HMO D-SNP) via Rebif	Tier 5 - Specialty	✓	—	—	PA

NC State Health Plan

3 plans

Source: PDF · Formulary date: Apr 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
NC State Health Plan - 80/20 Plus PPO 2026 via Avonex	Tier 5 - Preferred Brand Specialty	✓	—	✓	PA \| QL
NC State Health Plan - HDHP 2026 via Avonex	Tier 5 - Preferred Brand Specialty	✓	—	✓	PA \| QL
NC State Health Plan - 70/30 Standard PPO 2026 via Avonex	Tier 5 - Preferred Brand Specialty	✓	—	✓	PA \| QL

UnitedHealthcare

1 plan

Source: PDF · Formulary date: Jan 1, 2026 · Checked: 4 hours, 56 minutes ago

Plan	Tier	Prior Auth	Step Therapy	Quantity Limit	Restrictions
UnitedHealthcare NC Individual & Family 2026 via Avonex	Unknown	✓	—	✓	PA \| QL